Labyrinthitis Ossificans Post COVID Vaccination

Coronavirus disease 2019 is a highly infectious disease. The complications of the disease markedly reduced after the introduction of vaccine. Thus, vaccination for COVID-19 is important and has been prompted in many countries. Reports on rare serious adverse events after COVID-19 vaccinations are well documented. The audio vestibular adverse event after COVID-19 vaccination have been reported. We herein discussed a case of labyrinthitis ossificans post COVID vaccination. A 23-year-old male presented with sudden onset right hearing loss (SNHL) with tinnitus 3 days after received COVID-19 vaccine. Pure Tone Audiometry (PTA) revealed right profound hearing loss with normal left hearing. High Resolution Computed Tomography (HRCT) of the temporal bone showed hyperdensity seen at the basal turn of the right cochlea, with Magnetic Resonance Imaging (MRI) revealed focal loss of normal T2-weighted hyperintense signal intensity of the scala tympani of the basal turn of the cochlear, suggestive of labyrinthitis ossificans. He was fitted with hearing aid and undergone for right cochlear implant for hearing rehabilitation. Labyrinthitis ossificans is commonly caused by infection and inflammation, and less commonly trauma, tumors, hemorrhage, or autoimmune inner ear disease. The correlation with vaccination is yet to be revealed and required further study.