Biochemical Derangement in Twin Pregnancy: Complete Hydatidiform Mole and Viable Foetus
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Vol. 13 No. 2 : 2018 (180-187)
Abstract
Case of co-existence of twin pregnancy of complete hydatidiform molar with viable intrauterine pregnancy is extremely rare with low incidence of 1 case for 20,000 – 100,000. It is associated with high risk of spontaneous abortion, preterm delivery, intrauterine death, bleeding, pre-eclampsia, and persistence trophoblastic disease (PTD). It may associate with biochemical derangement that may induce population with significant clinical dilemma and management to the maternal and foetus. Here, we report a case of a young woman with previous bad obstetric history who presented with antepartum per-vaginal bleeding and was noted to have a twin pregnancy with complete hydatidiform molar and viable foetus. It was complicated with markedly elevated human chorionic gonadotropin (hCG) and hyperthyroidism. Postpartumly, her hCG level was persistently high and her condition progressed into gestational trophoblastic neoplasm.
Keywords :
complete hydatidiform molar,
human chorionic gonadotrophin,
hyperthyroid,
twin pregnancy,
Correspondance Address
Dr. Munirah Md Mansor. Chemical Pathology Unit,
Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan
Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia. Tel: +603-91459507 Email:
munirah.md.mansor@ppukm.ukm.edu.my
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