A 65-year-old male with a history of right-eye secondary orbital implant for anophthalmia socket with post-enucleation socket syndrome and no comorbidities presented a 5-day history of left eyelid redness and swelling. Progressive exacerbation ensued, accompanied by pain. On examination, the visual acuity of the left eye measured 6/12. Manifestations included a swollen, tender, erythematous lower lid and purulent ocular discharge. Notably, the middle third of the left lower lid displayed erosions and ulcerations with an overlay of necrotic tissue. Systemic and funduscopic examinations yielded unremarkable findings. The intervention involved debridement, wound desloughing and excision of the necrotic patch. Subsequent culture of purulent discharge revealed the presence of Pseudomonas aeruginosa. Intravenous antibiotics were administered according to microorganism sensitivity. Hematological investigations unveiled neutropenia, while subsequent comprehensive assessments excluded evidence of infectious, inflammatory, or hematological malignancies. Regrettably, the patient declined both bone marrow aspiration and trephine biopsy. After a 10-day inpatient observation, symptoms demonstrated marked improvement. Subsequent clinical follow-ups indicated complete symptom resolution without relapse. Urgent intervention comprising wound debridement and intravenous antibiotic therapy stands as imperative in necrotising fasciitis of the eyelid.