Three dimensional (3D) models mimic the features of native tissue environment.
Thus, morphology and signalling of cells from 3D culture are often more
physiological than routine two dimensional (2D) cell culture. It is also known
that the cell-secreted products have paracrine effect on other cells growth. In
this experimental study, we optimised the nasal fibroblast culture on a 3D cell
culture system and studied the effects of secretome from the 3D culture (3DCM)
